Publications

Books/Chapters
  1. D. Zhou, C. Wang, A. Hert, L. Yan, B. Dou, and L. Ouyang*, in Multicomponent HydrogelsSmart Materials for Biomedical Applications, ed. J. M. Dodda, K. Deshmukh, and D. Bezuidenhout, The Royal Society of Chemistry, 2023, ch. 8, pp. 231-287. [DOI] [PDF]
  1. L. Ouyang*, Study on Microextrusion-based 3D Bioprinting and Bioink Crosslinking Mechanisms (Springer, Singapore, 2019). ISBN 978-981-13-9455-3. [DOI] [PDF]
Journal Articles

(# equal contribution, * corresponding author)

Selected Articles (Metrics are as of 10/2024)

Video abstract of an invited review article: L. Ouyang*, Trends in Biotechnology, 40, 891-902 (2022). [DOI]

  • L. Ouyang et al, Expanding and Optimizing 3D Bioprinting Capabilities using Complementary Network Bioinks. Science Advances 6, eabc5529 (2020). [DOI] (Google引用>220次）
  • L. Ouyang et al, Void‐Free 3D Bioprinting for In Situ Endothelialization and Microfluidic Perfusion. Advanced Functional Materials 30, 1908349 (2020). [DOI] (Google引用>130次）
  • L. Ouyang et al, A Generalizable Strategy for The 3D Bioprinting of Hydrogels From Nonviscous Photo‐Crosslinkable Inks. Advanced Materials 29, 1604983 (2017). [DOI] (ESI高被引，Google引用>520次）
  • L. Ouyang et al, 3D Printing of Shear-thinning Hyaluronic Acid Hydrogels with Secondary Cross-linking. ACS Biomaterials Science & Engineering 2, 1743-1751 (2016). [DOI] (ESI高被引，Google引用>580次，期刊历史上引用量最高的研究论文[1/3000+]）
  • L. Ouyang et al, Effect of Bioink Properties on Printability and Cell Viability for 3D Bioplotting of Embryonic Stem Cells. Biofabrication 8, 035020 (2016). [DOI] (ESI高被引，Google引用>860次，期刊历史上引用量最高的研究论文[1/1000+]）
Full List of Articles
In progress
  1. C. Wang and L. Ouyang* et al., 2025 submitted.
  1. D. Zhou and L. Ouyang* et al., 2025 in revision.
  1. J. Ma and L. Ouyang* et al., 2025 in revision.
  1. R. Xu and L. Ouyang* et al., 2025 in revision.
2025
  1. Y. Guo Z. Wang, X. Zhang, J. Li, S. Gao, Y. Lv, L. Ouyang*, Microfiber-Templated Porogel Bioinks Enable Tubular Interfaces and Microvascularization Down to the Building Blocks for 3D Bioprinting. Small 2025 accepted.
  1. R. Xu, B. Dou, S. Yu, Z. Wang, Y. Zhang, L. Leng, L. Ouyang*, W. Sun, Enabling 3D printability and vascular morphogenesis with double network dynamic hydrogels. Materials Today 2025 in press. [DOI]
  1. D. Zhou, P. Li, S. Yu, Z. Cui, T. Xu, L. Ouyang*, Optimizing extrusion-based 3D bioprinting of plant cells with enhanced resolution and cell viability. Biofabrication, 17, 025008 (2025).[DOI] [PDF] [Supporting Information]
  1. P. Song, J. Chen, D. Zhao, K. Shi, R. Xu, M. Zhu, L. Zhao*, E.T. Pashuck, L. Ouyang, F. Jiao, Y. Lin*, Evolving Emulsion Microcompartments viaEnzyme-Mimicking Amyloid-Mediated Interfacial Catalysis. Small, 21, 2409601 (2025). [DOI] [PDF] [Supporting Information]
  1. B. Pei, J. Ma, L. Ouyang, Z. Xiong*, High-Security Data Encryption Enabled by DNA Multi-Strand Solid-Phase Hybridization and Displacement in Inkjet-Printed Microarrays. ACS Applied Materials & Interfaces, 17, 6, 10179–10190 (2025). [DOI] [PDF] [Supporting Information]
2024
  1. CK Chua*, J. An, S. Fan, X. Zhang, L. Ouyang*, H. Liu, L. Zhang, Y. Ren, M. Gou*, WL Ng, WY Yeong*, H. Zhu, Z. Meng, J. He*, A perspective on transformative bioprinting. International Journal of Bioprinting, 2024 in press. [DOI]
  1. B. Pei, Y. Zhou, Y. Yang, J. Ma, R. Cao, W. Huang, L. Ouyang, S. Mi, Z. Xiong*, A Novel DNA-based dual-mode data storage system with interrelated concise and detailed data. Small Science, 4, 2400094 (2024). [DOI] [PDF] [Supporting Information]
  1. X. Jia, X. Fan, C. Chen, Q. Lu, H. Zhou, Y. Zhao, X. Wang, S. Han, L. Ouyang, H. Yan, H. Dai*, H. Geng*, Chemical and structural engineering of gelatin-based delivery systems for therapeutic applications: a review. Biomacromolecules 25, 564-589 (2024). [DOI][PDF]
  1. Z. Zhou, J. Ji, J. He, T. Liu, L. Ouyang, W. Zhang, X. Zhang, Z. Zhang, K. Zhang, Y. Pang*, W. Sun*,  Harnessing three-dimensional in vitro systems to model immune responses to solid tumours: a step towards improving and creating personalized immunotherapies. Nature Reviews Immunology 24, 18-32 (2024). [DOI][PDF]
2023
  1. L. Ouyang*, M. Salmeron-Sanchez, Editorial 3D bioprinting and advanced biofabrication of biomaterials. Biomaterials Advances 156, 213725 (2023). [DOI][PDF]
  1. D. Zhou, B. Dou, F. Kroh, C. Wang, L Ouyang*, Biofabrication strategies with single-cell resolution: a review. International Journal of Extreme Manufacturing 5, 042005 (2023). [DOI][PDF]
  1. M. Ye, Y Shan, B Lu, H Luo, B Li, Y Zhang, Z Wang, Y Guo, L Ouyang, J Gu, Z Xiong*, T Zhang*, Creating a semi-opened micro-cavity ovary through sacrificial microspheres as an in vitro model for discovering the potential effect of ovarian toxic agents. Bioactive Materials 26, 216-230 (2023). [DOI][PDF][Supporting Information]
  1. P. Li, D. Zhou, C. Yang, W. Rao, F. Lin, L. Ouyang*, Advances in 3D Bioprinting: Additive Manufacturing of Living Cells from Animal, Plant, and Microbe. Journal of Mechanical Engineering 59, 237-252 (2023) [DOI][PDF]
2022
  1. D. Hachim, J. Zhao, J. Bhankharia, R. Nuñez-Toldra, L. Brito, H. Seong, M. Becce, L. Ouyang, C.L. Grigsby, S.G. Higgins, C.M. Terracciano, M.M. Stevens, Polysaccharide-polyplex nanofilm coatings enhance nanoneedle-based gene delivery and transfection efficiency. Small 18, 2202303 (2022). [DOI][PDF][Supporting Information]
  1. Y. Yang#, R. Xu#, C. Wang, Y. Guo, W. Sun*, L. Ouyang*, Recombinant Human Collagen-Based Bioinks for the 3D bioprinting of Full-thickness Human Skin Equivalent and Skin Tissue Engineering. International Journal of Bioprinting 8, 611 (2022). [DOI][PDF][Supporting Information]
  1. X. Mo, L. Ouyang, Z. Xiong*, T. Zhang*, Advances in Digital Light Processing of Hydrogels. Biomedical Materials 17, 042002 (2022). [DOI][PDF]
  1. C. Wang, Y. Yang, J. Ji, Y. Fang, L. Ouyang, L. Zhang*, W. Sun*, 3D-printed bioresorbable stent coated with dipyridamole-loaded nanofiber for restenosis prevention and endothelialization. International Journal of Bioprinting 8, 543 (2022). [DOI][PDF]
  1. X. Tian*, L. Wu, D. Gu, S. Yuan, Y. Zhao, X. Li, L. Ouyang, B. Song, T. Gao, J. He, X. Lin, F. Lin, J. Zhu, D. Li*, Roadmap for Additive Manufacturing: toward Intellectualization and Industrialization. Chinese Journal of Mechanical Engineering: Additive Manufacturing Frontiers (CJME-AMF) 1, 100014 (2022). [DOI] [PDF]
  1. Y. Fang#, Y. Guo#, T. Liu, R. Xu, S. Mao, X. Mo, T. Zhang, L. Ouyang*, Z. Xiong*, W. Sun, Advances in 3D Bioprinting. Chinese Journal of Mechanical Engineering: Additive Manufacturing Frontiers (CJME-AMF) 1, 100011 (2022). [DOI] [PDF]
  1. L. Ouyang*, J.P. Wojciechowski, J. Tang, Y. Guo, M.M. Stevens*, Tunable Microgel-Templated Porogel (MTP) Bioink for 3D Bioprinting Applications, Advanced Healthcare Materials, 11, 2200027 (2022). [DOI] [PDF] [Supporting Information] [Video1] Front Cover This Month in Pictures Feb 2022 Advanced Scinece News
  1. L. Ouyang*, Pushing the Rheological and Mechanical Boundaries of Extrusion-based 3D Bioprinting. Trends in Biotechnology, 40, 891-902 (2022). [DOI] [PDF] [Video1]
  1. H. Zhu, M. Monavari, K. Zheng, T. Distler, L. Ouyang, S. Heid, Z. Jin, J. He, D. Li, A.R. Boccaccini*, 3D Bio-printing of Multi-functional Dynamic Nanocomposite Bioinks incorporating Cudoped mesoporous bioactive glass nanoparticles for Bone Tissue Engineering. Small, 18, 2104996 (2022). [DOI] [PDF] [Supporting Information] [Video1] [Video2]
  1. Z. Fu, L. Ouyang*, R. Xu, Y. Yang, W. Sun*, Responsive Biomaterials for 3D Bioprinting: A Review. Materials Today 52, 112-132 (2022). [DOI] [PDF] Highlighted Paper
2021
  1. H. Hajiali*, L. Ouyang, V. Llopis-Hernandez, O. Dobred, F.R.A.J. Rose*, Review of Emerging Nanotechnology in Bone Regeneration: Progress, Challenges, and Perspectives. Nanoscale 13, 10266-10280 (2021). [DOI] [PDF]
  1. C. Li#, L. Ouyang#, J.P.K. Armstrong*, M.M. Stevens*, Advances in the Fabrication of Biomaterials for Gradient Tissue Engineering. Trends in Biotechnology 39, 150-164 (2021). [DOI] [PDF]
Before 2020
  1. Y. Fang, L. Ouyang, T. Zhang*, C. Wang, B. Lu, W. Sun, Optimizing Bifurcated Channels within an Anisotropic Scaffold for Engineering Vascularized Oriented Tissues. Advanced Healthcare Materials 9, 2000782 (2020). [DOI] [PDF] [Supporting Information]
  1. L. Ouyang, J.P.K. Armstrong, Y. Lin, J.P. Wojciechowski, C. Lee-Reeves, D. Hachin, K. Zhou, J.A. Burdick, M.M. Stevens*, Expanding and Optimizing 3D Bioprinting Capabilities using Complementary Network Bioinks. Science Advances 6, eabc5529 (2020). [DOI] [PDF] [Supporting Information]
  1. L. Ouyang, J.P.K. Armstrong, M. Salmeron‐Sanchez, M.M. Stevens*, Assembling Living Building Blocks to Engineer Complex Tissues. Advanced Functional Materials 30, 1909009 (2020). [DOI] [PDF]
  1. L. Ouyang, J.P.K. Armstrong, Q. Chen, Y. Lin, M.M. Stevens*, Void‐Free 3D Bioprinting for In Situ Endothelialization and Microfluidic Perfusion. Advanced Functional Materials 30, 1908349 (2020). [DOI] [PDF] [Supporting Information] [Video1] [Video2] [Video3] [Video4]
  1. C. Li, L. Ouyang, I.J. Pence, A.C. Moore, Y. Lin, C.W. Winter, J.P.K. Armstrong*, M.M. Stevens*, Buoyancy‐Driven Gradients for Biomaterial Fabrication and Tissue Engineering, Advanced Materials 31, 1900291 (2019). [DOI] [PDF] [Supporting Information] [Video1]
  1. L. Ouyang, J.A. Burdick, W. Sun*, Facile Biofabrication of Heterogeneous Multilayer Tubular Hydrogels by Fast Diffusion-induced Gelation. ACS Applied Materials & Interfaces 10, 12424-12430 (2018). [DOI] [PDF] [Supporting Information] [Video1]
  1. L. Ouyang, C.B. Highley, W. Sun, J.A. Burdick*, A Generalizable Strategy for The 3D Bioprinting of Hydrogels From Nonviscous Photo‐Crosslinkable Inks. Advanced Materials 29, 1604983 (2017). [DOI] [PDF] [Supporting Information] [Video1] [Video2] [Video3] [Video4] [Video5]
  1. Y.C. Yeh, L. Ouyang, C.B. Highley, J.A. Burdick*, Norbornene-modified Poly (glycerol sebacate) as A Photocurable and Biodegradable Elastomer. Polymer Chemistry 8, 5091-5099 (2017). [DOI] [PDF] [Video1]
  1. Y.C. Yeh#, C.B. Highley#, L. Ouyang, J.A. Burdick*, 3D Printing of Photocurable Poly (glycerol sebacate) Plastomers. Biofabrication 8, 045004 (2016). [DOI] [PDF]
  1. L. Ouyang#, C.B. Highley#, C.B. Rodell, W. Sun, J.A. Burdick*, 3D Printing of Shear-thinning Hyaluronic Acid Hydrogels with Secondary Cross-linking. ACS Biomaterials Science & Engineering 2, 1743-1751 (2016). [DOI] [PDF] [Supporting Information]
  1. L. Ouyang, R. Yao*, Y. Zhao, W. Sun, Effect of Bioink Properties on Printability and Cell Viability for 3D Bioplotting of Embryonic Stem Cells. Biofabrication 8, 035020 (2016). [DOI] [PDF] [Supporting Information]
  1. L. Ouyang#, R. Yao#, S. Mao, X. Chen, J. Na, W. Sun*, Three-dimensional bioprinting of embryonic stem cells directs highly uniform embryoid body formation. Biofabrication 7, 044101 (2015). [DOI] [PDF]
  1. L. Ouyang#, R. Yao#, X. Chen#, J. Na*, W. Sun*, 3D printing of HEK 293FT cell-laden hydrogel into macroporous constructs with high cell viability and normal biological functions. Biofabrication 7, 015010 (2015). [DOI] [PDF]
  1. Y. Zhao#, R. Yao#, L. Ouyang, H. Ding, T. Zhang, K. Zhang, S. Cheng, W. Sun*, Three-dimensional printing of Hela cells for cervical tumor model in vitro. Biofabrication 6, 035001 (2014). [DOI] [PDF]
  1. T. Zhang*, K.C. Yan, L. Ouyang, W. Sun, Mechanical Characterization of Bioprinted In Vitro Soft Tissue Models. Biofabrication 5, 045010 (2013). [DOI] [PDF]

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